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imagene microarray analysis software  (BioDiscovery Inc)

 
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    BioDiscovery Inc imagene microarray analysis software
    Imagene Microarray Analysis Software, supplied by BioDiscovery Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/imagene microarray analysis software/product/BioDiscovery Inc
    Average 90 stars, based on 1 article reviews
    imagene microarray analysis software - by Bioz Stars, 2026-06
    90/100 stars

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    Biogenesis of miRNAs. (A) In the nucleus, ribonuclease enzyme II transcribes the pri-miRNA transcript. Drosha and its co factor Pasha form the microprocessor complex that cleaves pri-miRNA transcript into pre-miRNA which share a stem loop structure. These pre-miRNAs are transported by exportin-5 into cytoplasm from nucleus. (B) In the cytoplasm, Dicer unwind the miRNA duplex into mature miRNA and complementary strand (miRNA*, which rapidly degraded), and loaded mature miRNA into RNA-induced silencing complex (RISC). (C) Depending on the degree of complementarity between the target mRNA and the miRNA, the binding ether stops the translation by cleaving the target mRNA or suppress translation by binding to impeding ribosomal reading of the mRNA (incomplete complementarity). miRNA, <t>microRNA;</t> pri-miRNA, primary microRNA; pre-miRNA, precursor -microRNA; RISC, RNA-induced silencing complex.
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    Image Search Results


    Biogenesis of miRNAs. (A) In the nucleus, ribonuclease enzyme II transcribes the pri-miRNA transcript. Drosha and its co factor Pasha form the microprocessor complex that cleaves pri-miRNA transcript into pre-miRNA which share a stem loop structure. These pre-miRNAs are transported by exportin-5 into cytoplasm from nucleus. (B) In the cytoplasm, Dicer unwind the miRNA duplex into mature miRNA and complementary strand (miRNA*, which rapidly degraded), and loaded mature miRNA into RNA-induced silencing complex (RISC). (C) Depending on the degree of complementarity between the target mRNA and the miRNA, the binding ether stops the translation by cleaving the target mRNA or suppress translation by binding to impeding ribosomal reading of the mRNA (incomplete complementarity). miRNA, microRNA; pri-miRNA, primary microRNA; pre-miRNA, precursor -microRNA; RISC, RNA-induced silencing complex.

    Journal: bioRxiv

    Article Title: Differentially deregulated microRNAs contribute to ultraviolet radiation-induced photocarcinogenesis through immunomodulation: An-analysis of microRNAs expression profiling

    doi: 10.1101/2023.02.24.529976

    Figure Lengend Snippet: Biogenesis of miRNAs. (A) In the nucleus, ribonuclease enzyme II transcribes the pri-miRNA transcript. Drosha and its co factor Pasha form the microprocessor complex that cleaves pri-miRNA transcript into pre-miRNA which share a stem loop structure. These pre-miRNAs are transported by exportin-5 into cytoplasm from nucleus. (B) In the cytoplasm, Dicer unwind the miRNA duplex into mature miRNA and complementary strand (miRNA*, which rapidly degraded), and loaded mature miRNA into RNA-induced silencing complex (RISC). (C) Depending on the degree of complementarity between the target mRNA and the miRNA, the binding ether stops the translation by cleaving the target mRNA or suppress translation by binding to impeding ribosomal reading of the mRNA (incomplete complementarity). miRNA, microRNA; pri-miRNA, primary microRNA; pre-miRNA, precursor -microRNA; RISC, RNA-induced silencing complex.

    Article Snippet: The miRCURY LNA ™ microRNA array slides were scanned using the Agilent G2565BA Microarray Scanner System (Agilent Technologies, Inc., USA), and the image analysis was carried out using the ImaGene ® 9 (miRCURY LNA ™ microRNA Array Analysis Software, Exiqon, Denmark).

    Techniques: Binding Assay